Best OTC Choices in Ophthalmic Decongestants

Drops of decongestant designed for your eyes can provide temporary relief from redness, burning and minor irritation. Here are Money’s picks for the best such ophthalmic decongestants, along with data on their active ingredients and general notes about their efficacy and side effects.

These products were selected by drugs.com, using a methodology that combines expert assessment with analysis of online reviews, ratings and other customer data.

The information provided on Money.com is for educational purposes only and is not intended as medical advice, diagnosis, or treatment. The products featured may not be right for everyone and may carry risk even if available without a prescription. Read the product’s label and consult with a professional for individual medical advice.

Slide Table to Compare
Rank
Medication
Active Ingredients
Important Points
#8
Bausch + Lomb Advanced Eye Relief Redness Naphazoline hcl Polyethylene glycol
  • Relieves redness
  • Lubricates eyes
  • Can use up to 4 times a day
#2
Clear Eyes Redness Relief Glycerin Naphazoline Hcl
  • Relieves redness
  • Can use up to 4 times a day
  • Lubricates the eye
#7
Equate Redness Reliever Tetrahydrozoline HCI
  • Relieves redness
  • Can use up to 4 times a day
  • Contains preservatives
#4
Naphcon-A Naphazoline hcl Pheniramine maleate
  • Safe in children 6 years and older
  • Relieves itching and redness
  • Can use up to 4 times a day
#3
Opcon-A Naphazoline hcl Pheniramine maleate
  • Safe in children 6 years and older
  • Relieves itching and redness
  • Can use up to 4 times a day
#6
Rohto Optic Glow Redness Reliever Lubricant Eye Drops Naphazoline hcl Povidone Propylene glycol
  • Can use up to 4 times daily
  • Works up to 8 hours
  • Relieves redness
  • Lubricates eyes
#5
Similasan Redness & Itchy Eye Relief Apis mellifica Euphrasia officinalis Euphrasia Schoenocaulon officinale Sabadilla Pulsatilla pratensis Pulsatilla
  • Homeopathic
  • Safe in children 1 year and older
  • Can use for up to 3 days
#1
Visine Red Eye Comfort Tetrahydrozoline hCI
  • Relieves redness
  • Safe in children 6 years and older
  • Can use up to 4 times a day
No results match.
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Featured drugs are available without a prescription in the U.S. and may not be available with or without a prescription in other locations.