Best OTC Drugs 2024

Best OTC Choices in Contact Lens Solutions, Saline

Unlike hydrogen peroxide contact-lens solutions, saline lens solutions do not disinfect. Rather, they’re formulated as a rinse for use before inserting the lenses into your eyes. Here are Money’s picks for the best saline contact-lens solutions, along with data on their active ingredients and other general notes about them.

These products were selected by, using a methodology that combines expert assessment with analysis of online reviews, ratings and other customer data.

The information provided on is for educational purposes only and is not intended as medical advice, diagnosis, or treatment. The products featured may not be right for everyone and may carry risk even if available without a prescription. Read the product’s label and consult with a professional for individual medical advice.

Slide Table to Compare
Active Ingredients
Important Points
Bausch + Lomb Biotrue Hyaluronan Polyaminopropyl biguanide Polyquaternium Alexidine
  • Provides additional moisture to lenses
  • Up to 20 hours of moisture
CVS Health Saline Saline
  • For soft contact lenses
  • Rinsing solution
Opti-Free Puremoist Polyquaternium Myristamidopropyl dimethylamine Polyoxyethylene polyoxybutylene
  • For silicone hydrogel and soft contact lenses
  • Must soak for at least 6 hours
  • Contains wetting agents
  • Can store lenses for up to 30 days
Refresh Carboxymethylcellulose sodium
  • Soothes dry contacts
  • Multidose bottle
  • For all soft and RGP contact lenses
Renu Poloxamine Polyaminopropyl biguanide Polyquaternium Alexidine
  • 3 different disinfectants
  • Provides up to 20 hours of moisture
Sensitive Eyes Saline
  • pH balanced
  • For rinsing soft contacts and gas permeable contacts
Walgreens Saline Saline
  • For soft contact lenses
  • Rinsing solution
No results match.

Featured drugs are available without a prescription in the U.S. and may not be available with or without a prescription in other locations.