Best OTC Drugs 2024

Best OTC Choices in Toothpaste, General Use

The best toothpastes are effective without being overly abrasive. Here are Money’s picks for the best toothpastes for general use. Most — with the exception of some pastes that boast natural ingredients — contain fluoride to strengthen tooth enamel. Our choices also include some brands that emphasize tooth whitening.

The selections were chosen by drugs.com, using a methodology that combines expert assessment with analysis of online reviews, ratings and other customer data.

The information provided on Money.com is for educational purposes only and is not intended as medical advice, diagnosis, or treatment. The products featured may not be right for everyone and may carry risk even if available without a prescription. Read the product’s label and consult with a professional for individual medical advice.

Slide Table to Compare
Rank
Medication
Active Ingredients
Important Points
#7
Aquafresh Cavity Protection Sodium fluoride
  • Safe for people 2 years and older
  • Prevents cavities
  • Contains dyes
#5
Arm & Hammer Advance White Sodium fluoride Sodium bicarbonate
  • Whitening
  • Safe for people 2 years and older
  • Prevents cavities
#10
Burt's Bees Purely White Toothpaste Glycerin Hydrated Silica
  • Fluoride-free
  • No artificial flavors or dyes
  • Whitening
#8
Close-Up Sodium fluoride
  • Safe for people 2 years and older
  • Prevents cavities
  • Contains dyes
#1
Colgate Total Stannous fluoride
  • 12 hour antibacterial protection
  • Safe for people 12 years and older
  • Prevents cavities
  • Whitening
#2
Crest Pro-Health Stannous fluoride
  • Safe for people 12 years and older
  • Prevents cavities
  • Whitening
#9
Hello Antiplaque and Whitening Toothpaste Sorbitol Hydrated silica Calcium carbonate Zinc citrate
  • Fluoride-free
  • Vegan
  • No artificial flavors or sweeteners
#6
Parodontax Complete Protection Stannous fluoride
  • Safe for people 2 years and older
  • Can use up to 3 times a day
  • Prevents cavities
#3
Sensodyne Pronamel Potassium nitrate Sodium fluoride
  • Safe for children 12 years and older
  • Reduces sensitivity
  • Whitening
#4
Tom's of Maine Whole Care Sodium monofluorophosphate
  • Vegan
  • No artifical sweeteners
  • Strengthens enamel
No results match.
TOP

Featured drugs are available without a prescription in the U.S. and may not be available with or without a prescription in other locations.