Best OTC Drugs 2024

Best OTC Choices in Toothpaste, Sensitive Gums/Teeth

Some people require a toothpaste that is gentler on their teeth and gums than regular formulations. Here are Money’s picks for the best toothpastes for sensitive mouths. Our choices also include a brand of tooth-whitening strips that emphasize sensitivity.

The selections were chosen by, using a methodology that combines expert assessment with analysis of online reviews, ratings and other customer data.

The information provided on is for educational purposes only and is not intended as medical advice, diagnosis, or treatment. The products featured may not be right for everyone and may carry risk even if available without a prescription. Read the product’s label and consult with a professional for individual medical advice.

Slide Table to Compare
Active Ingredients
Important Points
Arm & Hammer Sensitive Teeth and Gums Potassium nitrate Sodium fluoride
  • Safe for people 12 years and older
  • Should use twice a day
  • Prevents cavities
Colgate Sensitive Pro-Relief Calcium carbonate Arginine Sodium monofuorophosphate
  • Can apply directly to sensitive tooth for 1 minute
  • Prevents cavities
  • Long-lasting
Crest Sensi-Stop Strips Glycerin Dipotassium Oxalate Carbomer Sodium Hydroxide
  • Immediate relief
  • Must wear for 10 minutes
  • Shouldn't eat or drink for 30 minutes
Hello Sensitivity Relief Potassium nitrate Sodium fluoride
  • Vegan
  • No artifical sweeteners
  • Strengthens enamel
Oral-B Sensitivity & Gum Calm Stannous fluoride Sodium fluoride Eugenol
  • Safe for people 18 years and older
  • Relieves mouth pain
  • Prevents cavities
Parodontax Extra Fresh Sodium bicarbonate Glycerin Sodium fluoride
  • Helps stop bleeding gums
  • Can use up to 3 times a day
  • Safe for people 12 years and older
Sensodyne Pronamel Potassium nitrate Sodium fluoride
  • Safe for children 12 years and older
  • Reduces sensitivity
  • Whitening
Sensodyne Repair and Protect Stannous fluoride
  • Safe for people 12 years and older
  • Can use up to 3 times a day
  • Prevents cavities
Tom's of Maine Rapid Relief Sensitive Toothpaste Arginine bicarbonate Benzyl alcohol Calcium carbonate Hydrated silica
  • Fluoride-free
  • Long-lasting protection
  • No artificial dyes or sweeteners
No results match.

Featured drugs are available without a prescription in the U.S. and may not be available with or without a prescription in other locations.